| PUBLICATIONS (Ranked by Impact Factor of the Journal) | Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC To clarify how developmental and regional differences influence transformation, researchers transduced wild-type or mutationally stabilized murine N-mycT58A into neural stem cells from perinatal murine cerebellum, brain stem, and forebrain. [Cancer Cell] Abstract An Unconventional Role for miRNA: let-7 Activates Toll-Like Receptor 7 and Causes Neurodegeneration This study suggests that microRNAs (miRNAs) can function as signaling molecules and identifies Toll-like receptor 7 as an essential element in a pathway that contributes to the spread of central nervous system damage. [Nat Neurosci] Abstract Hepatocyte Growth Factor Mediates Mesenchymal Stem Cell-Induced Recovery in Multiple Sclerosis Models Researchers demonstrated that conditioned medium from human mesenchymal stem cells reduces functional deficits in mouse MOG35-55-induced experimental autoimmune encephalomyelitis and promotes the development of oligodendrocytes and neurons. [Nat Neurosci] Abstract A Dual Function of Bcl11b/Ctip2 in Hippocampal Neurogenesis The authors report that Bcl11b/Ctip2, a zinc finger transcription factor expressed in postmitotic neurons, plays a critical role during postnatal development of the dentate gyrus. [EMBO J] Full Article Intracerebral Chondroitinase ABC and Heparan Sulfate Proteoglycan Glypican Improve Outcome from Chronic Stroke in Rats Glypican and chondroitinase ABC reduced glial fibrillary acidic protein immunoreactivity and increased microtubule-associated protein-2 immunoreactivity in the periinfarct region, and glypican- and chondroitinase ABC-treated rats showed behavioral improvement compared with neurocan- or saline-treated rats. Glypican and chondroitinase ABC also increased neurite extension in cortical neuron cultures. [Proc Natl Acad Sci USA] Abstract | Press Release Full-Length Axon Regeneration in the Adult Mouse Optic Nerve and Partial Recovery of Simple Visual Behaviors Researchers showed that, with adequate stimulation, retinal ganglion cells are able to regenerate axons the full length of the visual pathway and on into the lateral geniculate nucleus, superior colliculus, and other visual centers. [Proc Natl Acad Sci USA] Abstract | Press Release Maladaptive Dendritic Spine Remodeling Contributes to Diabetic Neuropathic Pain To determine whether dendritic spine remodeling contributes to neuropathic pain in streptozotocin-induced diabetic rats, researchers analyzed dendritic spine morphology and electrophysiological and behavioral signs of neuropathic pain. [J Neurosci] Abstract | Press Release Conjugation of Functionalized SPIONs with Transferrin for Targeting and Imaging Brain Glial Tumors in Rat Model This study investigated the preparation and characterization of a targeted MR contrast agent, transferrin-conjugated superparamagnetic iron oxide nanoparticles (SPIONs) for brain glioma detection. [PLoS One] Full Article |
| JOB OPPORTUNITIES | Scientist – Endothelial Cells (STEMCELL Technologies, Inc.) Scientist – Induced Pluripotent Stem Cells (STEMCELL Technologies, Inc.) Scientist – Epithelial Cell Research (STEMCELL Technologies, Inc.) Scientist – Mesenchymal Cell Research (STEMCELL Technologies, Inc.) Business Analyst – Product Management (STEMSOFT Software, Inc.) Scientist – Antibody and Hybridoma Technology Platforms (STEMCELL Technologies, Inc.) Research Associate – Chemistry (STEMCELL Technologies, Inc.) Research Associate – Particle Chemistry (STEMCELL Technologies, Inc.) Research Technologist – Contract Assay Services (STEMCELL Technologies, Inc.) Postdoctoral Position – GIGA-Neurosciences (University of Liège) Postdoctoral Position – Spinal Cord Neural Stem Cells (Institute for Neurosciences of Montpellier) Assistant Professor – Neurology (Department of Neurology at Columbia University and the New York Presbyterian Hospital) Recruit Top Talent: Reach more than 50,000 potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost. |
|
|
|