 | | Vol. 11.24 – 3 July, 2020 |
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| Scientists mapped the RNA polymerase II-associated chromatin interactions in normal prostate cells and prostate cancer cells.
[Journal of Clinical Investigation] |
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 | | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors investigated the effect of exogenous chemerin on human prostate and sarcoma tumor lines. Key signaling pathway components were elucidated using qPCR, Western blotting, siRNA knockdown, and specific inhibitors.
[Clinical Cancer Research] |
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| Scientists found that KDM4B was overexpressed in enzalutamide-resistant prostate cancer cells. Overexpression of KDM4B promoted recruitment of androgen receptor to the c-Myc gene enhancer and induced H3K9 demethylation.
[Journal of Pathology] |
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| Functional effects of the four MiCaP miRNAs were assessed by overexpression and inhibition experiments in prostate cancer cell lines.
[Scientific Reports] |
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| Researchers report a novel synthetic lethal interaction between inhibitors of O-GlcNAc transferase and CDK9 that specifically killed prostate cancer cells but not normal cells.
[Molecular Cancer Research] |
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| Two different stabilized cell lines of androgen-resistant prostate cancer were treated with the conditioned media produced by extracorporeal shock waves-treated carcinoma-associated fibroblasts.
[Prostate] |
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| Investigators determined the anti-neoplastic activity of Cediranib, a pan-vascular endothelial growth factor receptor inhibitor, in the metastatic castration-resistant prostate cancer cell lines.
[European Journal of Pharmacology] |
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| Cell viability test was performed for the ceramics on Vero cells, and their antitumor activity was determined by a PC3 cell line.
[Life Sciences] |
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| Endothelial cells and epithelial cells were isolated from seven fresh human prostate tissue specimens and from primary tissue xenografts established from nine fresh human prostate tissue specimens.
[PLoS One] |
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| To imitate the relationship between cancer cells and tumor-associated macrophages, investigators co-cultured macrophages with etoposide-treated PC3 cells.
[Cell Biology International] |
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| The authors present publications demonstrating cytolytic properties against tumor cells of members belonging to the cecropin family, as well as synthesized cecropin B with the introduced modification of its sequence and conjugated cecropin B with a modified luteinizing hormone-releasing hormone.
[European Journal of Pharmacology] |
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| Ipsen announced it will join the Exelixis and Roche clinical collaboration and participate in the funding of the recently initiated CONTACT-01 and CONTACT-02 global Phase III pivotal trials.
[Ipsen Pharma] |
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| Academics in Hong Kong are facing new worries after the mainland government abruptly imposed a controversial new security law that critics say could infringe on human rights and chill academic freedom.
[ScienceInsider] |
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| The UK government plans to set up an “office for talent” to oversee visas and make it easier to attract top scientists after Brexit, according to an R&D road map.
[ScienceInsider] |
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| July 16 – July 17
Virtual |
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| | University of Maryland, Baltimore – Baltimore, Maryland, United States |
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| | Uniformed Services University of the Health Sciences – Bethesda, Maryland, United States |
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| | The Vita-Salute San Raffaele University – Milan, Italy |
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| | Berlin School of Integrative Oncology Charité – Berlin, Germany |
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| | University of Freiburg – Freiburg, Germany |
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