Autophagy in PDGFRα+ Mesenchymal Cells Is Essential for Intestinal Stem Cell Survival

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Autophagy was required for PDGFRα+ mesenchymal cells (PMC) metabolism and ileum stem cell and mammalian survival. Failure to maintain PMCs through autophagy may therefore contribute to inflammatory bowel diseases.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract