IFN-α/β-Mediated NK2R Expression Is Related to the Malignancy of Colon Cancer Cells

Researchers found that high neurokinin 2 receptor (NK2R) gene expression was correlated with the poor survival of colorectal cancer patients, and IFN-α/β stimulation significantly enhanced NK2R gene expression level of colon cancer cells in a JAK1/2-dependent manner.
[Cancer Science]
Abstract
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