The OmpA of Commensal Escherichia coli of CRC Patients Affects Apoptosis of the HCT116 Colon Cancer Cell Line
Scientists analyzed the effect of the Outer membrane protein A (OmpA) protein on the expression of the four genes related to apoptosis in the HCT116 colon cancer cell line.
[British Journal of Pharmacology] In vivo, investigators studied the role of Caspase-11 in several angiogenesis mouse models using Caspase-11 wild-type and knockout mice. In vitro, scientists detected the effects of Caspase-4 on endothelial functions and Notch signaling by depleting or overexpressing Caspase-4 in HUVECs.
[Proceedings of the National Academy of Sciences of the United States of America] Scientists identified the reversible SUMOylation of FGF receptor 1 (FGFR1) as an intrinsic fine-tuned mechanism in coordinating endothelial angiogenic signaling during neovascularization.