TCF7L2 Plays a Complex Role in Human Adipose Progenitor Biology, Which Might Contribute to Genetic Susceptibility to Type 2 Diabetes

Scientists mapped the expression of TCF7L2 in human adipose tissue (AT), examined its role in human adipose cell biology in vitro, and investigated the effects of the fine-mapped type 2 diabetes-risk allele at rs7903146 on AT morphology and TCF7L2 expression.