The Mechanism of the Imbalance Between Proliferation and Ferroptosis in Pulmonary Artery Smooth Muscle Cells Based on the Activation of SLC7A11

SLC7A11 was up-regulated in Sugen5416/hypoxia-induced pulmonary arterial hypertension (PAH) rats and patients with PAH. Moreover, solute carrier family 7 member 11 (SLC7A11) inhibited ferroptosis and promoted proliferation by overexpressing SLC7A11 in pulmonary artery smooth muscle cells.
[European Journal of Pharmacology]
Abstract
spot_img

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News