Overexpression of Laminin-5 Gamma-2 Promotes Tumorigenesis of Pancreatic Ductal Adenocarcinoma Through EGFR/ERK1/2/AKT/mTOR Cascade

Scientists reported that inhibition of Laminin-5 gamma-2 significantly decreased cell growth, clonogenic ability, migration, and invasion of PDAC cells and tumor growth in a PDAC xenograft model.