Prospects of Targeting PI3K/AKT/mTOR Pathway in Pancreatic Cancer

Scientists report that whole-genome analyses demonstrate the frequent involvement of aberrant activations of PI3K/AKT/mTOR pathway components in PDAC patients and critically evaluate preclinical and clinical evidence on the application of PI3K/AKT/mTOR pathway targeting agents.
[Critical Reviews in Oncology/Hematology]
AbstractGraphical Abstract

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