EZH2 Endorses Cell Plasticity to Non-Small Cell Lung Cancer Cells Facilitating Mesenchymal to Epithelial Transition and Tumor Colonization
The authors found that besides its described role in CDKN2A-dependent cell proliferation, EZH2 upheld the epithelial state of cancer cells by repressing the transcription of hundreds of mesenchymal genes.
[Haematologica] Myeloid-derived suppressor cells (MDSCs) populations were evaluated in acquired aplastic anemia in which aberrant immune mechanisms contributed to bone marrow destruction.
[Cell Death & Disease] To investigate the effect of ellagic acid (EA) on benign prostate hyperplasia, scientists used EA, a phytochemical abundant in fruits and vegetables, to treat testosterone propionate-induced BPH rats and RWPE-1 human prostate epithelial cells.