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e.g. organoids

Implementation of a Combined CDK Inhibition and Arginine-Deprivation Approach To Target Arginine-Auxotrophic Glioblastoma Multiforme Cells

Three arginine-auxotrophic patient-derived Glioblastoma multiforme (GBM) lines with different molecular characteristics were cultured in 2D and 3D and effects of this combined SpyADI/CDKi approach were analyzed in-depth.
[Cell Death & Disease]
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