Neuronal Hyperexcitability in Alzheimer’s Disease: What Are the Drivers Behind This Aberrant Phenotype?

The authors discuss contributors to aberrant neuronal excitability, including abnormal levels of intracellular Ca2+ and glutamate, pathological amyloid β (Aβ) and tau, genetic risk factors, including APOE, and impaired inhibitory interneuron and glial function.
[Translational Psychiatry]
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