Mice Lacking DCAF2 in Placenta Die at the Gastrulation Stage

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To clarify the function of DCAF2 in vivo, scientists used Cre recombinase driven by the Elf5 promoter to generate knockout mouse model that was specifically deleted Dcaf2 in the trophoblast lineage (Elf5-Cre; Dcaf2fl/fl, Dcaf2 cKO).
[Cell and Tissue Research]
Abstract