Glucocorticoid Signaling and Regulatory T Cells Cooperate to Maintain the Hair-Follicle Stem-Cell Niche

By using hair follicles (HFs) to study regulatory T cell cell–stem cell crosstalk, the authors showed an unrecognized function of the steroid hormone glucocorticoid in instructing skin-resident Treg cells to facilitate HF stem-cell activation and HF regeneration.