An Optimized Ionizable Cationic Lipid for Brain Tumor-Targeted siRNA Delivery and Glioblastoma Immunotherapy

A new cationic lipid nanoparticle that could efficiently deliver siRNA across blood-brain barrier and target mouse brain was prepared for modulating the tumor microenvironment for glioblastoma multiforme immunotherapy.
[Biomaterials]
AbstractGraphical Abstract
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