NewslettersHematopoiesis NewsRegulation of Erythropoiesis by the Hypoxia-Inducible Factor Pathway: Effects of Genetic and Pharmacological PerturbationsBy lbeveridge - July 5, 20220186Mutations in the genes encoding erythropoietin (EPO), EPO receptor, HIF-2α, prolyl hydroxylase domain protein 2, or von Hippel–Lindau protein caused familial erythrocytosis.[Annual Review of Medicine]Abstract