NewslettersCancer Stem Cell NewsMex3a Marks Drug-Tolerant Persister Colorectal Cancer Cells That Mediate Relapse after ChemotherapyBy lbeveridge - July 6, 20220595Patient-derived organoids expand from highly proliferative LGR5+ tumor cells; however, scientists discovered that lack of optimal growth conditions specified a latent LGR5+ cell state.[Nature Cancer]Abstract