CD95 Gene Deletion May Reduce Clonogenic Growth and Invasiveness of Human Glioblastoma Cells in a CD95 Ligand-Independent Manner

Researchers characterized CD95 and CD95L expression in human glioma-initiating cells, a glioblastoma cell population with stem cell features, and investigated the consequences of CRISPR-Cas9-mediated CD95 or CD95L gene deletion.