SLIT2 Promoter Hypermethylation-Mediated SLIT2-IT1/miR-218 Repression Drives Leukemogenesis and Predicts Adverse Prognosis in Myelodysplastic Neoplasm

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SLIT2 promoter methylation was markedly increased in myelodysplastic neoplasm/AML patients compared with controls and was correlated with poor clinical phenotype and outcome.
[Leukemia]
Abstract