Targeted Inhibition of Ubiquitin Signaling Reverses Metabolic Reprogramming and Suppresses Glioblastoma Growth

Using an integrated approach that includes proteomics, transcriptomics and metabolic profiling, scientists identified praja2, a RING E3 ubiquitin ligase, as the key component of a signaling network that regulates glioblastoma cell growth and metabolism.
[Communications Biology]
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