CFI-402257, a TTK Inhibitor, Effectively Suppresses Hepatocellular Carcinoma

Investigators reported that a newly developed, orally active small molecule inhibitor targeting threonine tyrosine kinase (TTK) effectively suppressed HCC growth and induced highly aneuploid HCC cells, DNA damage, and micronuclei formation.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract
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