Thymidine Kinase 1 Mediates the Synergistic Antitumor Activity of Ubenimex and Celecoxib via Regulation of Cell Cycle in Colorectal Cancer

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Scientists revealed that ubenimex and/or celecoxib exerted anti–colon cancer effects in vitro and in vivo, and the efficacy was significantly enhanced when the two drugs were combined.
[Journal of Pharmacology and Experimental Therapeutics]
Abstract