Hypoxia-Induced HMGB1 Promotes Glioma Stem Cells Self-Renewal and Tumorigenicity via RAGE

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Investigators reported that high mobility group box 1 (HMGB1) was overexpressed in human glioblastoma specimens. Hypoxia promoted the expression and secretion of HMGB1 in glioma stem cells
[iScience]
Abstract