NewslettersProstate Cell NewsA Genome-Wide CRISPR-Cas9 Knockout Screen Identifies Novel PARP Inhibitor Resistance Genes in Prostate CancerBy lbeveridge - August 12, 20220325The authors generated multiple knockout populations per gene in C4 and/or LNCaP CRPC cells, which confirmed that loss of PARP1, ARH3, YWHAE, or UBR5 caused olaparib resistance.[Oncogene]Full Article