Investigation of the Effect of Meclofenamic Acid on the Proteome of LNCaP Cells Reveals Changes in Alternative Polyadenylation and Splicing Machinery
Meclofenamic acid, a non-steroidal anti-inflammatory drug, with anti-tumor effects in various types of cancers, was used to investigate its effects on LNCaP cells, a prostate cancer cell line, at the proteome level.
[Journal of Hazardous Materials] The toxicity of particulate material to fibroblast cells derived from the human dermis was investigated using metabolomic analysis for the class of amino acids.
[Journal of Investigative Dermatology] Using two mouse genetic models and human and mouse cell lines, the authors found that the inactivation of Dicer in melanocytes led to a misplacement of these cells within the hair follicle.