Oncolytic Virus–Mediated p53 Overexpression Promotes Immunogenic Cell Death and Efficacy of PD-1 Blockade in Pancreatic Cancer

Scientists investigated the therapeutic potential of p53-expressing telomerase-specific oncolytic adenovirus OBP-702 to induce immunogenic cell death and antitumor immune responses in human pancreatic ductal adenocarcinoma cells with different p53 status.
[Molecular Therapy Oncolytics]
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