A Proliferative to Invasive Switch Is Mediated by srGAP1 Downregulation Through the Activation of TGF-β2 Signaling

Scientists identified srGAP1 as a regulator of a proliferative-to-invasive switch in breast cancer cells, and high-resolution light-sheet microscopy demonstrated that these cells could switch form actin-rich protrusions during extravasation.
[Cell Reports]
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