Glial Cell Derived Neurotrophic Factor Prevents Western Diet and Palmitate-Induced Hepatocyte Oxidative Damage and Death through SIRT3

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Researchers found that western diet (WD)-feeding increased hepatic lipid peroxidation in control mice and, ,in vitro palmitate induced oxidative stress and impaired the mitophagic clearance of damaged mitochondria in hepatocytes.
[Scientific Reports]
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