Novel Histone Deacetylase 6 Inhibitor Confers Anti-Inflammatory Effects and Enhances Gut Barrier Function

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The effects of CKD-506 on gut barrier function in a cell line and colon organoids, based on examinations of mRNA production, goblet cell differentiation, and E-cadherin recovery, were investigated using quantitative reverse transcription PCR, immunofluorescence, and a fluorescein isothiocyanate-dextran permeability assay.
[Gut and Liver]
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