Mechanism of RIP2 Enhancing Stemness of Glioma Cells Induces Temozolomide Resistance.

Cancer stemness of glioma cells was investigated by sphere formation assays, clone formation assays, and xenograft tumor formation assays. The expression of RIP2, p-NF-κB, IκBα, CD133, or SOX-2 was detected by Western blotting and immunofluorescence.