Meis1 Supports Leukemogenesis through Stimulation of Ribosomal Biogenesis and Myc

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While HoxA9 alone immortalizes cells, cooperation with Meis1 is necessary to induce a full leukemic phenotype. Here, the authors applied degron techniques to elucidate the leukemogenic contribution of Meis1.
[Haematologica]
Abstract