LncRNA PVT-1 Promotes Osteosarcoma Cancer Stem-Like Properties through Direct Interaction with TRIM28 and TSC2 Ubiquitination

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Scientists demonstrated that Plasmacytoma Variant Translocation-1 (PVT-1) was critical for osteosarcoma tumor-initiation potential, further elucidating the role of PVT-1 in the enhancement of cancer stem-like behaviors
[Oncogene]
Abstract