Biomimetic Extracellular Matrix Nanofibers Electrospun with Calreticulin Promote Synergistic Activity for Tissue Regeneration

The authors incorporated calreticulin (CRT) via polyblend electrospinning into polycaprolactone/type 1 collagen nanofibers as biomimetic ECMs to provide a novel mode of delivery and protection of CRT with enhanced synergistic activities for tissue regeneration.