The Long Noncoding RNA TINCR Promotes Self-Renewal of Human Liver Cancer Stem Cells through Autophagy Activation
TINCR was found to be highly expressed in HCC tissues and liver cancer stem cells (LCSCs). In vitro and in vivo assays for the first time showed that TINCR was required for LCSC self-renewal and tumorigenesis.
[Prostate Cancer Foundation] The Prostate Cancer Foundation announced four inaugural Class of 2022 TACTICAL Award recipients. This $30 million program will support cross-disciplinary pioneering research toward the goal of developing 21st Century therapies for the most life-threatening form of prostate cancer.
[Nature Communications] Researchers reported high levels of androgen receptor chromatin binding heterogeneity in human primary prostate tumors, that overlapped with heterogeneity observed in healthy prostate epithelium.