GZMK^high CD8⁺ T Effector Memory Cells Are Associated with CD15^high Neutrophil Abundance in Non-Metastatic Colorectal Tumors and Predict Poor Clinical Outcome

Scientists found that colorectal cancer tumors highly infiltrated by neutrophils contained a population of CD8+ TEM cells characterized by high levels of Granzyme K, which led to a worse prognosis.