Single-Cell Profiling of Vascular Endothelial Cells Reveals Progressive Organ-Specific Vulnerabilities during Obesity
Scientists used single-cell RNA sequencing to analyze transcriptomes of ~375,000 endothelial cells from seven organs in male mice at progressive stages of obesity to identify organ-specific vulnerabilities.
[Prostate Cancer Foundation] The Prostate Cancer Foundation announced four inaugural Class of 2022 TACTICAL Award recipients. This $30 million program will support cross-disciplinary pioneering research toward the goal of developing 21st Century therapies for the most life-threatening form of prostate cancer.
[Nature Communications] Researchers reported high levels of androgen receptor chromatin binding heterogeneity in human primary prostate tumors, that overlapped with heterogeneity observed in healthy prostate epithelium.