Responses of INS-1 Cells to Glucose Stimulation Patterns
Altered material properties of the INS-1 cells revealed the regulation of multiple glucose stimulation patterns. Rapidly responding to high glucose, INS-1 cells presented the unique meshing networks of elasticities.
[Nature Communications] Using computational tools, organoids, and spatial tools, the authors showed that LY6D+ basosquamous cells represented a persister population lying on a central node along the skin lineage-associated spectrum of epithelial states.
[Nature Communications] Scientists identified a cohort of early-stage colorectal tumors, with aggressive features and a propensity to disseminate early, that were characterized by high epithelial cell-intrinsic TGFβ signaling.