Isocitrate Dehydrogenase 1 Mutation Drives Leukemogenesis by PDGFRA Activation Due to Insulator Disruption in Acute Myeloid Leukemia (AML)

Using public RNA-Seq data, investigators identified upregulation of tyrosine kinase PDGFRA in IDH1-mutant patients, correlating with poor prognosis.
[Leukemia]
Full ArticleGraphical Abstract
spot_img

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News