Isocitrate Dehydrogenase 1 Mutation Drives Leukemogenesis by PDGFRA Activation Due to Insulator Disruption in Acute Myeloid Leukemia (AML)

Using public RNA-Seq data, investigators identified upregulation of tyrosine kinase PDGFRA in IDH1-mutant patients, correlating with poor prognosis.
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