Superenhancer-Activation of KLHDC8A Drives Glioma Ciliation and Hedgehog Signaling

Scientists interrogated superenhancer landscapes of primary glioblastoma specimens and patient-derived GSCs, revealing a kelch domain-containing gene (KLHDC8A) with a previously unknown function as an epigenetically-driven oncogene.
[Journal of Clinical Investigation]
AbstractGraphical Abstract
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