BNIP3-Dependent Mitophagy Safeguards ESC Genomic Integrity via Preventing Oxidative Stress-Induced DNA Damage and Protecting Homologous Recombination

Researchers showed that BNIP3-dependent mitophagy protected genomic integrity in mESCs. Deletion of Bnip3 increased cellular reactive oxygen species and decreased ATP generation.
[Cell Death & Disease]
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