Elevation of Cell-Associated HIV-1 Transcripts in CSF CD4+ T Cells, despite Effective Antiretroviral Therapy, Is Linked to Brain Injury

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Researchers investigated cell-associated-HIV-1 RNA transcripts in cells in cerebrospinal fluid and blood, using the highly sensitive Double-R assay, together with proton Magnetic Resonance Spectroscopy of major brain metabolites, in sixteen people living with HIV-1 infection.
[Proceedings of the National Academy of Sciences of the United States of America]
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