CD147 Contributes to SARS-CoV-2-Induced Pulmonary Fibrosis

Investigators systemically analyzed lung pathogenesis in SARS-CoV-2- and its delta variant-infected humanized CD147 transgenic mice. Histopathology and Transmission Electron Microscopy revealed inflammation, fibroblast expansion and pronounced fibrotic remodeling in SARS-CoV-2-infected lungs.
[Signal Transduction and Targeted Therapy]
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