High Antibody Levels and Reduced Cellular Response in Children up to One Year After SARS-CoV-2 Infection

Four months after infection, children showed an enhanced specific antibody response and lower but detectable spike 1 protein (S1)-specific B and T cell responses, compared to their parents. One year after infection, an increase in the S1-specific IgA class switched, and the expression of CD27 on S1-specific B cells and T cell maturation were observed.