GL-V9 Alleviates Liver Fibrosis via Triggering GATA4-Mediated Senescence in Activated Hepatic Stellate Cells

Bile duct ligation and carbon tetrachloride challenge were used to assess anti-fibrotic effects of GL-V9 in vivo. Mouse primary hepatic stellate cells and human HSC line LX2 also served as an in vitro liver fibrosis model.