The Influenza-Injured Lung Microenvironment Promotes MRSA Virulence, Contributing to Severe Secondary Bacterial Pneumonia

By conditioning Staphylococcus aureus (MRSA) ex vivo in bronchoalveolar lavage fluid collected from mice at various time points of influenza infection, investigators found that the influenza-injured lung microenvironment dynamically induced MRSA to increase cytotoxin expression, while decreasing metabolic pathways.