NRP1 Inhibition Modulates Radiosensitivity of Medulloblastoma by Targeting Cancer Stem Cells

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Neuropilin-1 receptor (NRP1) inhibition with a novel peptidomimetic agent, MR438, was evaluated with radiotherapy in medulloblastoma models in vitro on cancer stem-like cells as well as in vivo on heterotopic and orthotopic xenografts.
[Cancer Cell International]
Abstract