Mutual Regulation between Phosphofructokinase 1 Platelet Isoform and Vegf Promotes Glioblastoma Tumor Growth

Scientists showed that phosphofructokinase 1 platelet isoform could promote EGFR activation-induced vascular endothelial growth factor (VEGF) expression in HIF-1α-dependent and -independent manners in glioblastoma cells.