OGT Controls Mammalian Cell Viability by Regulating the Proteasome/mTOR/ Mitochondrial Axis

Investigators performed a genome-wide CRISPR–Cas9 screen in mESCs to identify candidates whose depletion rescued the block in cell proliferation induced by O-GlcNAc transferase (OGT) deficiency.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
AbstractPress Release

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