Safety and Efficacy of Injection of Human Placenta Mesenchymal Stem Cells Derived Exosomes for Treatment of Complex Perianal Fistula in Non-Crohn’s Cases: Clinical Trial Phase I

Researchers evaluated the safety of MSC-derived exosomes application for complex perianal fistula. Placenta-derived MSCs were cultured and exosomes were isolated using ultracentrifugation.