BMX Controls 3βHSD1 and Sex Steroid Biosynthesis in Cancer

Researchers showed that phosphorylation of tyrosine 344 occured and was required for 3β-hydroxysteroid dehydrogenase-1 (3βHSD1) cellular activity and generation of Δ4, 3-keto-substrates of 5α-reductase and aromatase, including in patient tissues.